Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Nc
Flybase description The gene Nedd2-like caspase is referred to in FlyBase by the symbol Dmel\Nc (CG8091, FBgn0026404).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.9147 -1.582 -2.877688 -1.822 -3.754845 -2.0034 -2.94414 -3.687954
    Affimetrix absolute value 6.868 6.959 6.691 7.523 6.903 7.567 7.029 6.436
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: endopeptidase activity; cysteine-type endopeptidase activity; protein homodimerization activity.
There is experimental evidence for 19 unique biological process terms, many of which group under: programmed cell death; cell death; system development; protein maturation; biological regulation; gland morphogenesis; sensory organ development; neuron differentiation; gene expression; salivary gland morphogenesis.
67 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; organ system subdivision; external compound sense organ; peripheral nervous system; cell part; embryonic/larval excretory system; imaginal precursor; adult segment; adult; pigment cell; acellular anatomical structure; cell projection.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Caspase, interleukin-1 beta convertase; DEATH-like; Peptidase C14, ICE, catalytic subunit p20; Peptidase C14, ICE, catalytic subunit p20, active site; Peptidase C14, caspase catalytic; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14, caspase precursor p45; Peptidase C14, caspase precursor p45, core.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed at stages throughout the pupal period.