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|Flybase description||The gene Nedd2-like caspase is referred to in FlyBase by the symbol Dmel\Nc (CG8091, FBgn0026404).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: endopeptidase activity; cysteine-type endopeptidase activity; protein homodimerization activity.
There is experimental evidence for 19 unique biological process terms, many of which group under: programmed cell death; cell death; system development; protein maturation; biological regulation; gland morphogenesis; sensory organ development; neuron differentiation; gene expression; salivary gland morphogenesis.
67 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; organ system subdivision; external compound sense organ; peripheral nervous system; cell part; embryonic/larval excretory system; imaginal precursor; adult segment; adult; pigment cell; acellular anatomical structure; cell projection.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Caspase, interleukin-1 beta convertase; DEATH-like; Peptidase C14, ICE, catalytic subunit p20; Peptidase C14, ICE, catalytic subunit p20, active site; Peptidase C14, caspase catalytic; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14, caspase precursor p45; Peptidase C14, caspase precursor p45, core.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed at stages throughout the pupal period.