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|Flybase description||This gene is referred to in FlyBase by the symbol Dmel\Lim1 (CG11354, FBgn0026411).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: leg disc proximal/distal pattern formation; positive regulation of transcription, DNA-dependent; imaginal disc-derived leg morphogenesis; negative regulation of transcription, DNA-dependent.
26 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system subdivision; adult segment; appendage segment; organ system; thoracic segment; integumentary plate; adult uniglomerular antennal lobe projection neuron vPN; metatarsus; unguis; mesothoracic preepisternum; antennal lobe projection neuron vPN.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Zinc finger, LIM-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 06-24 hour embryonic stages, during early pupal stages.