Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Eaat1
Flybase description The gene Excitatory amino acid transporter 1 is referred to in FlyBase by the symbol Dmel\Eaat1 (CG3747, FBgn0026439).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.7087 6.3405 1.626654 -54.2142 -55.935029 -28.8396 -4.76517 0.053248
    Affimetrix absolute value 9.15 10.175 8.842 2.718 3.027 3.772 6.304 7.988
    Affymetric present call in "x" number of chips 3 3 3 1 2 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; L-aspartate transmembrane transporter activity.
There is experimental evidence that it is involved in the biological process: determination of adult lifespan; regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction.
12 alleles are reported.
The phenotypes of these alleles are annotated with: neuromuscular junction; neuropil; dopaminergic neuron; adult neuromuscular junction; synapse.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Sodium:dicarboxylate symporter; Sodium:dicarboxylate symporter, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed during late pupal stages.