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|Flybase description||The gene Axin is referred to in FlyBase by the symbol Dmel\Axn (CG7926, FBgn0026597).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: beta-catenin binding; protein kinase binding.
There is experimental evidence that it is involved in the biological process: imaginal disc pattern formation; eye-antennal disc morphogenesis; somatic stem cell maintenance; negative regulation of Wnt receptor signaling pathway; oogenesis; imaginal disc-derived wing morphogenesis; Wnt receptor signaling pathway; phagocytosis, engulfment.
40 alleles are reported.
The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; adult segment; organ system subdivision; thoracic segment; portion of tissue; acellular anatomical structure; tracheal system; indirect flight muscle; adult; external compound sense organ.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: Axin beta-catenin binding; DIX; Regulator of G protein signalling; Regulator of G protein signalling superfamily; Regulator of G-protein signaling, domain 1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.