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|Flybase description||This gene is referred to in FlyBase by the symbol Dmel\CG1516 (FBgn0027580).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: pyruvate carboxylase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: pyruvate metabolic process.
14 alleles are reported.
No phenotypic data is available.
It has 11 annotated transcripts and 11 annotated polypeptides.
Protein features are: ATP-grasp fold; ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; Aldolase-type TIM barrel; Biotin carboxylase, C-terminal; Biotin carboxylation domain; Biotin-binding site; Biotin/lipoyl attachment; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carboxylase, conserved domain; Pre-ATP-grasp fold; PreATP-grasp-like fold; Pyruvate carboxylase; Pyruvate carboxyltransferase; Rudiment single hybrid motif; Single hybrid motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed during early larval stages, during late pupal stages.