Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG1516
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG1516 (FBgn0027580).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 7.9452 6.1548 3.779033 2.0199 2.928454 1.3702 4.86164 3.972567
    Affimetrix absolute value 11.366 10.209 9.997 9.351 10.25 9.016 10.818 10.095
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: pyruvate carboxylase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: pyruvate metabolic process.
14 alleles are reported.
No phenotypic data is available.
It has 11 annotated transcripts and 11 annotated polypeptides.
Protein features are: ATP-grasp fold; ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; Aldolase-type TIM barrel; Biotin carboxylase, C-terminal; Biotin carboxylation domain; Biotin-binding site; Biotin/lipoyl attachment; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carboxylase, conserved domain; Pre-ATP-grasp fold; PreATP-grasp-like fold; Pyruvate carboxylase; Pyruvate carboxyltransferase; Rudiment single hybrid motif; Single hybrid motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression.
Peak expression observed during early larval stages, during late pupal stages.