Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG31012
Flybase description The gene CIN85 and CD2AP orthologue is referred to in FlyBase by the symbol Dmel\cindr (CG31012, FBgn0027598).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.0391 -1.4941 -2.147471 -2.0008 -3.362221 -2.3769 -3.711 -2.669349
    Affimetrix absolute value 6.432 7.051 7.078 7.406 7.042 7.364 6.704 6.848
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: SH3 domain binding.
There is experimental evidence that it is involved in the biological process: positive regulation of receptor-mediated endocytosis; border follicle cell migration; compound eye development; lateral inhibition; intercellular bridge organization; cytokinesis; actin filament organization; compound eye morphogenesis.
19 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: external compound sense organ; organ system; organ system subdivision; peripheral nervous system; adult; portion of tissue; epithelial cell; intercellular bridge; organelle; actin cytoskeleton; extracellular region; primary pigment cell.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Neutrophil cytosol factor 2 p67phox; Src homology-3 domain; Variant SH3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed during early pupal stages.