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|Flybase description||The gene CIN85 and CD2AP orthologue is referred to in FlyBase by the symbol Dmel\cindr (CG31012, FBgn0027598).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: SH3 domain binding.
There is experimental evidence that it is involved in the biological process: positive regulation of receptor-mediated endocytosis; border follicle cell migration; compound eye development; lateral inhibition; intercellular bridge organization; cytokinesis; actin filament organization; compound eye morphogenesis.
19 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: external compound sense organ; organ system; organ system subdivision; peripheral nervous system; adult; portion of tissue; epithelial cell; intercellular bridge; organelle; actin cytoskeleton; extracellular region; primary pigment cell.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Neutrophil cytosol factor 2 p67phox; Src homology-3 domain; Variant SH3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed during early pupal stages.