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|Flybase description||The gene 6-phosphofructo-2-kinase is referred to in FlyBase by the symbol Dmel\Pfrx (CG3400, FBgn0027621).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: fructose-2,6-bisphosphate 2-phosphatase activity; 6-phosphofructo-2-kinase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: fructose metabolic process.
34 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has 11 annotated transcripts and 11 annotated polypeptides.
Protein features are: 6-phosphofructo-2-kinase; Bifunctional 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphate 2-phosphatase; Fructose-2,6-bisphosphatase; Histidine phosphatase superfamily, clade-1; Phosphoglycerate/bisphosphoglycerate mutase, active site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 18-24 hour embryonic stages, in stages of adults of both sexes.