Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name c(2)M
Flybase description The gene crossover suppressor on 2 of Manheim is referred to in FlyBase by the symbol Dmel\c(2)M (CG4249, FBgn0028525).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.53 -30.3163 -46.783775 -53.6989 -70.060214 -57.2219 -64.16568 -46.185271
    Affimetrix absolute value 2.957 2.706 2.658 2.662 2.64 2.725 2.548 2.717
    Affymetric present call in "x" number of chips 0 1 0 1 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: reciprocal meiotic recombination; meiosis; resolution of meiotic recombination intermediates.
15 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Rad21/Rec8-like protein, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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