Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name A3-3
Flybase description The gene Activating transcription factor 3 is referred to in FlyBase by the symbol Dmel\Atf3 (CG11405, FBgn0028550).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.3308 1.3456 -2.067944 -0.3502 -4.180693 -1.1097 1.49313 -3.113503
    Affimetrix absolute value 8.007 8.035 7.276 8.359 6.904 8.415 9.104 6.806
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: nervous system development.
16 alleles are reported.
The phenotypes of these alleles are annotated with: eye; embryonic/larval fat body.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Basic-leucine zipper (bZIP) transcription factor; Fos transforming protein; bZIP transcription factor, bZIP-1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 18-24 hour embryonic stages.