Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fab1
Flybase description This gene is referred to in FlyBase by the symbol Dmel\fab1 (CG6355, FBgn0028741).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -31.4733 -11.7205 -16.965204 -12.465 -23.570155 -11.1106 -20.51549 -22.152838
    Affimetrix absolute value 3.451 4.081 4.225 4.799 4.269 5.099 4.223 3.862
    Affymetric present call in "x" number of chips 0 0 1 3 2 3 2 0
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: 1-phosphatidylinositol-3-phosphate 5-kinase activity.
There is experimental evidence that it is involved in the biological process: endosome to lysosome transport; phosphatidylinositol phosphorylation.
6 alleles are reported.
The phenotype of these alleles is annotated with: eye disc.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Chaperonin Cpn60/TCP-1; DEP domain; Phosphatidylinositol-4-phosphate 5-kinase, core; Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup; Winged helix-turn-helix transcription repressor DNA-binding; Zinc finger, FYVE-related; Zinc finger, FYVE-type; Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.
This gene is annotated by FlyBase as a dicistronic gene, meaning that some or all of its transcripts encode two or more polypeptide-coding open reading frames (ORFs) , with each ORF assigned to a different gene.
The distribution of RNA-Seq coverage data amongst the different encoded genes cannot be determined.