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|Flybase description||The gene nicotinic Acetylcholine Receptor α 34E is referred to in FlyBase by the symbol Dmel\nAcRα-34E (CG32975, FBgn0028875).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: acetylcholine binding; nicotinic acetylcholine-activated cation-selective channel activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ion transport.
9 alleles are reported.
No phenotypic data is available.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Neurotransmitter-gated ion-channel, conserved site; Nicotinic acetylcholine receptor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages.