Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Spt6
Flybase description The gene Spt6 is referred to in FlyBase by the symbol Dmel\Spt6 (CG12225, FBgn0028982).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.4424 -1.0897 -1.635457 -2.4277 -2.909353 -2.4292 -2.20125 -2.607436
    Affimetrix absolute value 6.633 7.495 7.495 7.137 7.242 7.286 7.442 6.916
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: chromatin binding.
There is experimental evidence that it is involved in the biological process: transcription from RNA polymerase II promoter; regulation of antimicrobial peptide biosynthetic process.
8 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Nucleic acid-binding, OB-fold; Nucleic acid-binding, OB-fold-like; RNA-binding domain, S1; Ribosomal protein S1, RNA-binding domain; SH2 motif; Tex RuvX-like domain; Tex-like domain; Transcription elongation factor Spt6; YqgF/RNase H-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.