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|Flybase description||The gene Serpin 27A is referred to in FlyBase by the symbol Dmel\Spn27A (CG11331, FBgn0028990).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: enzyme inhibitor activity; serine-type endopeptidase inhibitor activity.
There is experimental evidence that it is involved in the biological process: defense response to fungus; defense response to insect; negative regulation of proteolysis; melanization defense response; Toll signaling pathway; negative regulation of melanization defense response; response to wounding; dorsal/ventral axis specification; melanotic encapsulation of foreign target; behavioral response to ethanol.
15 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic epidermis; wing; embryonic dorsal epidermis.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protease inhibitor I4, serpin; Protease inhibitor I4, serpin, conserved site; Serpin domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed at stages throughout the pupal period.