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| Gene name | Spn27A | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Serpin 27A is referred to in FlyBase by the symbol Dmel\Spn27A (CG11331, FBgn0028990). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: enzyme inhibitor activity; serine-type endopeptidase inhibitor activity. There is experimental evidence that it is involved in the biological process: defense response to fungus; defense response to insect; negative regulation of proteolysis; melanization defense response; Toll signaling pathway; negative regulation of melanization defense response; response to wounding; dorsal/ventral axis specification; melanotic encapsulation of foreign target; behavioral response to ethanol. 15 alleles are reported. The phenotypes of these alleles are annotated with: embryonic epidermis; wing; embryonic dorsal epidermis. It has one annotated transcript and one annotated polypeptide. Protein features are: Protease inhibitor I4, serpin; Protease inhibitor I4, serpin, conserved site; Serpin domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout the pupal period. . |
