Flygut: an atlas of the Drosophila adult midgut

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Gene name Spn27A
Flybase description The gene Serpin 27A is referred to in FlyBase by the symbol Dmel\Spn27A (CG11331, FBgn0028990).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.6316 -1.4819 -17.829932 -19.4419 -26.915693 -18.3545 -4.35005 -5.947218
    Affimetrix absolute value 10.208 7.053 4.031 4.148 4.019 4.372 6.472 5.684
    Affymetric present call in "x" number of chips 3 3 0 0 0 0 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: enzyme inhibitor activity; serine-type endopeptidase inhibitor activity.
There is experimental evidence that it is involved in the biological process: defense response to fungus; defense response to insect; negative regulation of proteolysis; melanization defense response; Toll signaling pathway; negative regulation of melanization defense response; response to wounding; dorsal/ventral axis specification; melanotic encapsulation of foreign target; behavioral response to ethanol.
15 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic epidermis; wing; embryonic dorsal epidermis.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protease inhibitor I4, serpin; Protease inhibitor I4, serpin, conserved site; Serpin domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed at stages throughout the pupal period.
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