Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name cathD
Flybase description The gene cathD is referred to in FlyBase by the symbol Dmel\cathD (CG1548, FBgn0029093).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 10.3178 11.0044 10.018911 15.1125 7.554839 8.4597 5.8589 9.754834
    Affimetrix absolute value 11.77 11.078 11.497 12.298 11.67 11.626 11.076 11.515
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: aspartic-type endopeptidase activity.
There is experimental evidence that it is involved in the biological process: apoptosis; nurse cell apoptosis; autophagic cell death; salivary gland cell autophagic cell death.
8 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Peptidase A1; Peptidase aspartic; Peptidase aspartic, active site; Peptidase aspartic, catalytic; Propeptide, peptidase A1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.