Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name debcl
Flybase description The gene death executioner Bcl-2 homologue is referred to in FlyBase by the symbol Dmel\debcl (CG33134, FBgn0029131).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.2575 -1.2554 -5.404381 -4.1692 -7.373538 -3.995 -2.62303 -3.801483
    Affimetrix absolute value 8.079 7.297 5.754 6.342 5.91 6.586 7.171 6.317
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: apoptosis; induction of apoptosis; negative regulation of neuron apoptosis; DNA damage response, signal transduction resulting in induction of apoptosis.
22 alleles are reported.
The phenotypes of these alleles are annotated with: eye disc; eye; salivary gland; interommatidial bristle; eye photoreceptor cell; wing; ommatidium; pigment cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Apoptosis regulator, Bcl-2, BH; Apoptosis regulator, Bcl2-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.