Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ssh
Flybase description The gene slingshot is referred to in FlyBase by the symbol Dmel\ssh (CG6238, FBgn0029157).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.1571 -6.4417 -9.360074 -10.5294 -13.321783 -12.5249 -12.10376 -12.33947
    Affimetrix absolute value 5.094 4.936 4.975 5.041 5.044 4.919 4.958 4.682
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein tyrosine/serine/threonine phosphatase activity.
There is experimental evidence that it is involved in the biological process: mitotic cell cycle; regulation of axonogenesis; regulation of lamellipodium assembly; compound eye development; mushroom body development; regulation of actin polymerization or depolymerization.
14 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; wing hair; denticle belt.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: DEK, C-terminal; Dual specificity phosphatase, catalytic domain; Dual specificity phosphatase, subgroup, catalytic domain; Protein-tyrosine phosphatase, active site; Protein-tyrosine/Dual-specificity phosphatase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes.