Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Aos1
Flybase description The gene Aos1 is referred to in FlyBase by the symbol Dmel\Aos1 (CG12276, FBgn0029512).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.5502 -1.6379 -1.809608 -2.0472 -1.766477 -1.5689 -2.31602 -1.828046
    Affimetrix absolute value 7.776 6.909 7.328 7.357 7.94 7.927 7.345 7.382
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: positive regulation of NF-kappaB transcription factor activity; neurogenesis.
8 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Molybdenum cofactor biosynthesis, MoeB; NAD(P)-binding domain; UBA/THIF-type NAD/FAD binding fold; Ubiquitin/SUMO-activating enzyme E1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.