Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name RhoGAP5A
Flybase description The gene RhoGAP5A is referred to in FlyBase by the symbol Dmel\RhoGAP5A (CG3208, FBgn0029778).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.1783 -5.64 -6.67208 -9.9027 -10.798517 -8.6061 -10.86212 -8.00622
    Affimetrix absolute value 6.037 5.123 5.454 5.092 5.347 5.471 5.127 5.263
    Affymetric present call in "x" number of chips 3 0 0 1 2 3 2 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: diacylglycerol binding.
There is experimental evidence that it is involved in the biological process: regulation of MAPKKK cascade; adherens junction maintenance; compound eye development; cell-cell adhesion.
5 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Diacylglycerol/phorbol-ester binding; N-chimaerin; Protein kinase C-like, phorbol ester/diacylglycerol binding; Rho GTPase activation protein; Rho GTPase-activating protein domain; SH2 motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.