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|Flybase description||This gene is referred to in FlyBase by the symbol Dmel\CG4096 (FBgn0029791).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: metalloendopeptidase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: proteolysis.
3 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: ADAM-TS Spacer 1; Metallopeptidase, catalytic domain; Peptidase M12B, ADAM-TS; Peptidase M12B, ADAM/reprolysin; Peptidase M12B, propeptide; Thrombospondin, type 1 repeat.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.