Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name CG3011
Flybase description This gene is referred to in FlyBase by the symbol Dmel\CG3011 (FBgn0029823).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.4982 1.214 -1.19828 -0.2982 -1.40792 -0.6224 -0.52843 -0.420114
    Affimetrix absolute value 10.189 7.874 7.932 8.427 8.289 8.247 8.339 8.13
    Affymetric present call in "x" number of chips 3 3 1 3 3 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: glycine hydroxymethyltransferase activity.
There is experimental evidence that it is involved in the biological process: behavioral response to ethanol.
4 alleles are reported.
The phenotype of these alleles is annotated with: trichogen cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Pyridoxal phosphate-dependent transferase, major domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Serine hydroxymethyltransferase; Serine hydroxymethyltransferase, pyridoxal phosphate binding site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed at stages throughout the larval period, at stages throughout the pupal period, in adult female stages.