Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Grip
Flybase description The gene Glutamate receptor binding protein is referred to in FlyBase by the symbol Dmel\Grip (CG14447, FBgn0029830).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.2449 -12.7588 -16.919558 -15.405 -18.242436 -11.6765 -12.8922 -16.216681
    Affimetrix absolute value 5.782 3.957 4.103 4.468 4.629 5.057 4.864 4.262
    Affymetric present call in "x" number of chips 2 2 2 2 2 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; receptor binding.
There is experimental evidence that it is involved in the biological process: muscle organ morphogenesis; protein import into nucleus, translocation; determination of muscle attachment site; muscle attachment; synapse organization.
32 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; hypodermal muscle of larval abdomen; multicellular structure; larval abdominal segment; embryonic/larval hypodermal muscle; adult; anatomical structure; synapse; abdominal 6 oblique muscle; hypodermal muscle of larval abdominal 2; presynaptic active zone.
It has one annotated transcript and one annotated polypeptide.
Protein features are: PDZ/DHR/GLGF.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 06-24 hour embryonic stages.