Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name spirit
Flybase description The gene Serine Protease Immune Response Integrator is referred to in FlyBase by the symbol Dmel\spirit (CG2056, FBgn0030051).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.6404 -4.1675 -22.36457 -24.882 -36.894674 -32.1942 -8.62109 -13.932564
    Affimetrix absolute value 6.6 5.573 3.715 3.766 3.557 3.561 5.626 4.464
    Affymetric present call in "x" number of chips 3 3 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions There is not condition-dependent expression data available for this gene.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: serine-type endopeptidase activity.
There is experimental evidence that it is involved in the biological process: defense response to fungus; innate immune response; defense response to Gram-positive bacterium; defense response to Gram-negative bacterium; positive regulation of Toll signaling pathway.
3 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Disulphide knot CLIP; Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, chymotrypsin-type; Peptidase cysteine/serine, trypsin-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed during late larval stages, during early pupal stages.