Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name tomosyn
Flybase description The gene tomosyn is referred to in FlyBase by the symbol Dmel\tomosyn (CG17762, FBgn0030412).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -7.6721 -1.7672 -4.144349 -3.9796 -5.440574 -4.2037 -4.11856 -5.177978
    Affimetrix absolute value 5.502 6.81 6.154 6.408 6.357 6.521 6.543 5.927
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: syntaxin-1 binding.
There is experimental evidence that it is involved in the biological process: neurogenesis.
9 alleles are reported.
The phenotype of these alleles is annotated with: intersegmental nerve.
It has 7 annotated transcripts and 7 annotated polypeptides.
Protein features are: Lethal giant larvae homologue 2; Lethal(2) giant larvae protein; Synaptobrevin; WD40 repeat; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.