Flygut: an atlas of the Drosophila adult midgut

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Gene name Lig4
Flybase description The gene Ligase4 is referred to in FlyBase by the symbol Dmel\Lig4 (CG12176, FBgn0030506).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -14.7095 -4.8223 -4.92413 -8.6109 -8.953897 -8.533 -15.12423 -8.450477
    Affimetrix absolute value 4.553 5.362 5.879 5.297 5.617 5.51 4.658 5.183
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: telomere maintenance; response to ionizing radiation; double-strand break repair via nonhomologous end joining.
9 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: BRCT; DNA ligase, ATP-dependent; DNA ligase, ATP-dependent, C-terminal; DNA ligase, ATP-dependent, N-terminal; DNA ligase, ATP-dependent, central; Nucleic acid-binding, OB-fold; Nucleic acid-binding, OB-fold-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, at stages throughout the pupal period, in stages of adults of both sexes.