Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name RhoGAP15B
Flybase description The gene RhoGAP15B is referred to in FlyBase by the symbol Dmel\RhoGAP15B (CG4937, FBgn0030808).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.8065 -2.4588 -3.615072 -4.9239 -6.784621 -3.7311 -11.66514 -4.805901
    Affimetrix absolute value 4.98 6.335 6.345 6.155 6.017 6.673 5.02 6.02
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: small GTPase regulator activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: signal transduction.
3 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Pleckstrin homology domain; Pleckstrin homology-type; Rho GTPase activation protein; Rho GTPase-activating protein domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages.