Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Frq1
Flybase description The gene Frequenin 1 is referred to in FlyBase by the symbol Dmel\Frq1 (CG5744, FBgn0030897).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.2835 -28.6894 -51.62517 -59.4326 -62.440973 -36.4396 -61.83739 -53.360175
    Affimetrix absolute value 4.797 2.832 2.493 2.498 2.808 3.384 2.609 2.532
    Affymetric present call in "x" number of chips 3 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: calcium ion binding; calcium sensitive guanylate cyclase activator activity.
There is experimental evidence that it is involved in the biological process: synaptic transmission; neurotransmitter secretion; neuromuscular junction development.
7 alleles are reported.
The phenotypes of these alleles are annotated with: NMJ bouton; embryonic/larval neuromuscular junction; type I bouton.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Calcium-binding EF-hand; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand; EF-hand-like domain; Recoverin.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages.