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|Flybase description||The gene HERC2 is referred to in FlyBase by the symbol Dmel\HERC2 (CG11734, FBgn0031107).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: ubiquitin-protein ligase activity; guanyl-nucleotide exchange factor activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: protein ubiquitination.
2 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Anaphase-promoting complex, subunit 10/DOC domain; CPH domain; CUB; Cytochrome b5; Galactose-binding domain-like; HECT; Mib-herc2; Regulator of chromosome condensation, RCC1; Regulator of chromosome condensation/beta-lactamase-inhibitor protein II; Translation protein SH3-like, subgroup; UBA-like; Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.