Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Ntf-2
Flybase description The gene Nuclear transport factor-2 is referred to in FlyBase by the symbol Dmel\Ntf-2 (CG1740, FBgn0031145).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.4311 -1.3135 -1.867757 -1.7546 -2.844383 -1.7455 -1.31924 -2.034684
    Affimetrix absolute value 7.893 7.239 7.281 7.593 7.259 7.763 8.169 7.228
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein transmembrane transporter activity.
There is experimental evidence that it is involved in the biological process: positive regulation of antimicrobial peptide biosynthetic process.
17 alleles are reported.
The phenotypes of these alleles are annotated with: eye; mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Nuclear transport factor 2; Nuclear transport factor 2, Eukaryote.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.