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|Flybase description||The gene Signal peptide protease is referred to in FlyBase by the symbol Dmel\Spp (CG11840, FBgn0031260).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: aspartic endopeptidase activity, intramembrane cleaving.
There is experimental evidence that it is involved in the biological process: membrane protein proteolysis; open tracheal system development.
16 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; heart primordium; embryonic/larval tracheal system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Peptidase A22, presenilin signal peptide; Peptidase A22B, signal peptide peptidase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-18 hour embryonic stages, during early larval stages.