Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name nAcRbeta-21C
Flybase description The gene nicotinic acetylcholine receptor beta 21C is referred to in FlyBase by the symbol Dmel\nAcR╬▓-21C (CG11822, FBgn0031261).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -32.636 -11.6577 -23.283651 -35.2065 -39.661134 -38.0153 -37.83319 -22.176646
    Affimetrix absolute value 3.399 4.102 3.638 3.296 3.451 3.314 3.318 3.84
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: nicotinic acetylcholine-activated cation-selective channel activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: ion transport.
6 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Neurotransmitter-gated ion-channel; Neurotransmitter-gated ion-channel ligand-binding; Neurotransmitter-gated ion-channel transmembrane domain; Nicotinic acetylcholine receptor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages, during late pupal stages, in adult male stages.
.