Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name iHog
Flybase description The gene interference hedgehog is referred to in FlyBase by the symbol Dmel\ihog (CG9211, FBgn0031872).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -16.5797 -13.8437 -22.069142 -33.6974 -45.899192 -31.9519 -21.26731 -30.198601
    Affimetrix absolute value 4.36 3.831 3.742 3.37 3.27 3.574 4.19 3.398
    Affymetric present call in "x" number of chips 1 3 1 0 0 0 2 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: heparin binding; protein binding; hedgehog receptor activity; protein homodimerization activity.
There is experimental evidence that it is involved in the biological process: smoothened signaling pathway; regulation of smoothened signaling pathway; cuticle pattern formation; positive regulation of smoothened signaling pathway; wing disc pattern formation.
19 alleles are reported.
The phenotype of these alleles is annotated with: wing.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.