Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Pvf2
Flybase description The gene PDGF- and VEGF-related factor 2 is referred to in FlyBase by the symbol Dmel\Pvf2 (CG13780, FBgn0031888).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -15.6761 -13.1569 -20.041161 -20.1468 -23.54535 -23.5864 -19.76434 -20.264452
    Affimetrix absolute value 4.462 3.936 3.887 4.064 4.222 4.053 4.269 3.903
    Affymetric present call in "x" number of chips 1 1 0 0 0 2 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: vascular endothelial growth factor receptor binding.
There is experimental evidence that it is involved in the biological process: hemocyte migration; hemocyte proliferation; salivary gland morphogenesis.
14 alleles are reported.
The phenotypes of these alleles are annotated with: plasmatocyte; adult midgut; intestinal stem cell; enterocyte; hemocyte; crystal cell; embryonic hemocyte.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period.