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|Flybase description||The gene PDGF- and VEGF-receptor related is referred to in FlyBase by the symbol Dmel\Pvr (CG8222, FBgn0032006).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transmembrane receptor protein tyrosine kinase activity; protein binding.
There is experimental evidence for 15 unique biological process terms, many of which group under: cellular component organization or biogenesis; localization; biological regulation; cellular component movement; regulation of developmental process; actin filament-based process; hemopoiesis; hemopoietic or lymphoid organ development; immune system process; response to DNA damage stimulus; immune response; gland morphogenesis; organelle organization; ventral cord development; post-embryonic organ morphogenesis; system development; digestive tract development.
62 alleles are reported.
The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; portion of tissue; sense organ; adult segment; epithelial cell; thoracic segment; embryonic/larval hemocoel; eo support cell; Kc167 cell-line.
It has 11 annotated transcripts and 11 annotated polypeptides.
Protein features are: Immunoglobulin I-set; Immunoglobulin V-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.