Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Pvr
Flybase description The gene PDGF- and VEGF-receptor related is referred to in FlyBase by the symbol Dmel\Pvr (CG8222, FBgn0032006).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.6205 -0.3834 -1.717456 -1.8918 -3.410898 -2.4424 -2.09847 -2.357662
    Affimetrix absolute value 7.022 7.556 7.428 7.49 7.034 7.294 7.526 7.087
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transmembrane receptor protein tyrosine kinase activity; protein binding.
There is experimental evidence for 15 unique biological process terms, many of which group under: cellular component organization or biogenesis; localization; biological regulation; cellular component movement; regulation of developmental process; actin filament-based process; hemopoiesis; hemopoietic or lymphoid organ development; immune system process; response to DNA damage stimulus; immune response; gland morphogenesis; organelle organization; ventral cord development; post-embryonic organ morphogenesis; system development; digestive tract development.
62 alleles are reported.
The phenotypes of these alleles are annotated with 24 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; portion of tissue; sense organ; adult segment; epithelial cell; thoracic segment; embryonic/larval hemocoel; eo support cell; Kc167 cell-line.
It has 11 annotated transcripts and 11 annotated polypeptides.
Protein features are: Immunoglobulin I-set; Immunoglobulin V-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period.