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|Flybase description||The gene Hand is referred to in FlyBase by the symbol Dmel\Hand (CG18144, FBgn0032209).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: larval heart development; negative regulation of apoptosis; hemopoiesis; embryonic heart tube development.
27 alleles are reported.
The phenotypes of these alleles are annotated with: lymph gland derived hemocyte; embryonic/larval pericardial cell; alary cell; embryonic/larval heart; lymph gland primordium; cardioblast; embryonic pericardial cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-24 hour embryonic stages, during early pupal stages.