Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name RluA-2
Flybase description The gene RluA-2 is referred to in FlyBase by the symbol Dmel\RluA-2 (CG6187, FBgn0032256).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.325 -8.0301 -10.717617 -13.9703 -16.700062 -15.9682 -17.81952 -17.601091
    Affimetrix absolute value 4.933 4.627 4.759 4.618 4.72 4.578 4.429 4.19
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: pseudouridine synthesis.
5 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Pseudouridine synthase, RluC/RluD; Pseudouridine synthase, RluC/RluD, conserved site; Pseudouridine synthase, RsuA and RluB/C/D/E/F; Pseudouridine synthase, catalytic domain; RNA-binding S4.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed at stages throughout embryogenesis, in adult female stages.