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|Flybase description||The gene RluA-2 is referred to in FlyBase by the symbol Dmel\RluA-2 (CG6187, FBgn0032256).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: pseudouridine synthesis.
5 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Pseudouridine synthase, RluC/RluD; Pseudouridine synthase, RluC/RluD, conserved site; Pseudouridine synthase, RsuA and RluB/C/D/E/F; Pseudouridine synthase, catalytic domain; RNA-binding S4.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed at stages throughout embryogenesis, in adult female stages.