Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name sNPF
Flybase description The gene short neuropeptide F precursor is referred to in FlyBase by the symbol Dmel\sNPF (CG13968, FBgn0032840).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -26.2152 -3.8485 -29.507812 -54.5056 -74.651443 -58.8108 -69.03096 -24.143195
    Affimetrix absolute value 3.703 5.816 3.298 2.621 2.545 2.689 2.444 3.666
    Affymetric present call in "x" number of chips 3 3 1 0 0 0 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: neuropeptide hormone activity.
There is experimental evidence that it is involved in the biological process: larval feeding behavior; regulation of trehalose metabolic process; determination of adult lifespan; positive regulation of cell size; positive regulation of insulin receptor signaling pathway; regulation of glucose metabolic process; positive regulation of ERK1 and ERK2 cascade; multicellular organism growth; adult feeding behavior; positive regulation of multicellular organism growth.
13 alleles are reported.
The phenotype of these alleles is annotated with: embryonic/larval fat body.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period, in adult male stages.