Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Nup44A
Flybase description The gene Nucleoporin 44A is referred to in FlyBase by the symbol Dmel\Nup44A (CG8722, FBgn0033247).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.6136 -2.2087 -2.637024 -3.0006 -2.958128 -2.9915 -3.30029 -2.572305
    Affimetrix absolute value 7.024 6.479 6.779 6.806 7.199 6.997 6.836 6.877
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: structural constituent of nuclear pore.
There is experimental evidence that it is involved in the biological process: regulation of meiotic cell cycle; regulation of mitotic cell cycle; oogenesis.
9 alleles are reported.
The phenotypes of these alleles are annotated with: centriole; eye; trichogen cell; oocyte; mesothoracic tergum; egg chamber; microtubule; germarium.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: G-protein beta WD-40 repeat; WD40 repeat; WD40 repeat 2; WD40 repeat, subgroup; WD40 repeat-like-containing domain; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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