Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Socs44A
Flybase description The gene Suppressor of Cytokine Signaling at 44A is referred to in FlyBase by the symbol Dmel\Socs44A (CG2160, FBgn0033266).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.0842 1.4592 1.259377 -1.2122 -1.336288 -0.4185 -3.32346 -0.547344
    Affimetrix absolute value 7.35 8.153 8.499 8.12 8.35 8.452 6.843 7.998
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: positive regulation of epidermal growth factor receptor signaling pathway; negative regulation of JAK-STAT cascade.
4 alleles are reported.
The phenotype of these alleles is annotated with: wing vein L3.
It has one annotated transcript and one annotated polypeptide.
Protein features are: SH2 motif; SOCS protein, C-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages.