Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name tsu
Flybase description The gene tsunagi is referred to in FlyBase by the symbol Dmel\tsu (CG8781, FBgn0033378).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.3559 -1.1172 -1.270754 -1.2342 -1.307244 -0.3554 -1.30218 -1.290817
    Affimetrix absolute value 8.437 7.459 7.836 8.093 8.376 8.531 8.179 7.875
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: mRNA binding.
There is experimental evidence that it is involved in the biological process: oocyte anterior/posterior axis specification; oocyte nucleus migration involved in oocyte dorsal/ventral axis specification; epidermal growth factor receptor signaling pathway; regulation of pole plasm oskar mRNA localization; microtubule cytoskeleton organization; oocyte dorsal/ventral axis specification.
16 alleles are reported.
The phenotypes of these alleles are annotated with: egg; egg chamber; oocyte nucleus; dorsal appendage.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; RNA-binding motif protein 8.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.