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|Flybase description||The gene Matrix metalloproteinase 2 is referred to in FlyBase by the symbol Dmel\Mmp2 (CG1794, FBgn0033438).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: metalloendopeptidase activity.
There is experimental evidence that it is involved in the biological process: tracheal pit formation in open tracheal system; negative regulation of fibroblast growth factor receptor signaling pathway; lateral inhibition; basement membrane disassembly; tracheal outgrowth, open tracheal system; imaginal disc fusion, thorax closure; imaginal disc eversion; basement membrane organization; oogenesis; open tracheal system development.
118 alleles are reported.
The phenotypes of these alleles are annotated with: interommatidial bristle; adult thorax; ommatidium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Hemopexin/matrixin; Hemopexin/matrixin, repeat; Metallopeptidase, catalytic domain; Peptidase M10, metallopeptidase; Peptidase M10A, matrix metallopeptidase; Peptidase, metallopeptidase; Peptidoglycan binding-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed during early pupal stages.