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|Flybase description||The gene eiger is referred to in FlyBase by the symbol Dmel\egr (CG12919, FBgn0033483).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: immune response; asymmetric protein localization involved in cell fate determination; melanization defense response; induction of apoptosis; JNK cascade; defense response to Gram-negative bacterium; apical protein localization.
16 alleles are reported.
The phenotypes of these alleles are annotated with: eye; embryonic/larval optic stalk; adult abdomen; wing; scutellum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Tumour necrosis factor; Tumour necrosis factor, conserved site; Tumour necrosis factor-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages.