Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name egr
Flybase description The gene eiger is referred to in FlyBase by the symbol Dmel\egr (CG12919, FBgn0033483).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.5646 -1.383 -15.164789 -28.2258 -26.510215 -3.9983 -22.67609 -14.130673
    Affimetrix absolute value 4.663 7.166 4.383 3.591 4.106 6.58 4.072 4.539
    Affymetric present call in "x" number of chips 2 3 1 0 0 3 2 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: immune response; asymmetric protein localization involved in cell fate determination; melanization defense response; induction of apoptosis; JNK cascade; defense response to Gram-negative bacterium; apical protein localization.
16 alleles are reported.
The phenotypes of these alleles are annotated with: eye; embryonic/larval optic stalk; adult abdomen; wing; scutellum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Tumour necrosis factor; Tumour necrosis factor, conserved site; Tumour necrosis factor-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during early pupal stages.
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