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|Flybase description||The gene Derailed 2 is referred to in FlyBase by the symbol Dmel\Drl-2 (CG3915, FBgn0033791).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: receptor signaling protein tyrosine kinase activity.
There is experimental evidence that it is involved in the biological process: Wnt receptor signaling pathway; salivary gland morphogenesis.
10 alleles are reported.
The phenotypes of these alleles are annotated with: presumptive embryonic salivary gland; antennal lobe glomerulus VL1; glomerulus; antennal lobe glomerulus VM7; antennal lobe.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; WIF domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages.