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|Flybase description||The gene O-fucosyltransferase 1 is referred to in FlyBase by the symbol Dmel\O-fut1 (CG12366, FBgn0033901).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Notch binding; fucosyltransferase activity.
There is experimental evidence that it is involved in the biological process: negative regulation of Notch signaling pathway; endocytosis; lateral inhibition; regulation of Notch signaling pathway; cell-cell adhesion; nervous system development; protein catabolic process.
31 alleles are reported.
The phenotypes of these alleles are annotated with: wing margin; leg; eye; S2 cell-line; chaeta; wing; wing vein.
It has one annotated transcript and one annotated polypeptide.
Protein features are: GDP-fucose protein O-fucosyltransferase.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, during early pupal stages.