Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name cpa
Flybase description The gene capping protein alpha is referred to in FlyBase by the symbol Dmel\cpa (CG10540, FBgn0034577).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.0037 5.4269 3.778322 6.3203 2.6832 4.0759 1.58748 3.902838
    Affimetrix absolute value 9.405 10.048 10.087 11.035 10.174 10.558 9.213 10.176
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: actin binding.
There is experimental evidence that it is involved in the biological process: germarium-derived oocyte fate determination; wing disc development; regulation of lamellipodium assembly; actin cytoskeleton organization; negative regulation of actin filament polymerization; actin filament organization; negative regulation of filopodium assembly; phagocytosis, engulfment.
15 alleles are reported.
The phenotypes of these alleles are annotated with: eye; wing disc; macrochaeta; wing hinge primordium; wing.
It has one annotated transcript and one annotated polypeptide.
Protein features are: F-actin capping protein, alpha subunit, conserved site; WASH complex, F-actin capping protein, alpha subunit.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed during early pupal stages.