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|Flybase description||The gene capping protein alpha is referred to in FlyBase by the symbol Dmel\cpa (CG10540, FBgn0034577).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: actin binding.
There is experimental evidence that it is involved in the biological process: germarium-derived oocyte fate determination; wing disc development; regulation of lamellipodium assembly; actin cytoskeleton organization; negative regulation of actin filament polymerization; actin filament organization; negative regulation of filopodium assembly; phagocytosis, engulfment.
15 alleles are reported.
The phenotypes of these alleles are annotated with: eye; wing disc; macrochaeta; wing hinge primordium; wing.
It has one annotated transcript and one annotated polypeptide.
Protein features are: F-actin capping protein, alpha subunit, conserved site; WASH complex, F-actin capping protein, alpha subunit.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed during early pupal stages.