Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name synj
Flybase description The gene synaptojanin is referred to in FlyBase by the symbol Dmel\synj (CG6562, FBgn0034691).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.5831 -1.9523 -2.863729 -3.1168 -5.716958 -3.4114 -3.21966 -4.26349
    Affimetrix absolute value 7.039 6.684 6.682 6.77 6.286 6.803 6.916 6.221
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: inositol-polyphosphate 5-phosphatase activity.
There is experimental evidence that it is involved in the biological process: synaptic vesicle endocytosis; maintenance of presynaptic active zone structure; regulation of synapse structure and activity.
13 alleles are reported.
The phenotype of these alleles is annotated with: presynaptic active zone.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Domain of unknown function DUF1866; Endonuclease/exonuclease/phosphatase; Inositol polyphosphate-related phosphatase; Nucleotide-binding, alpha-beta plait; Synaptojanin, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes.