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|Flybase description||The gene synaptojanin is referred to in FlyBase by the symbol Dmel\synj (CG6562, FBgn0034691).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: inositol-polyphosphate 5-phosphatase activity.
There is experimental evidence that it is involved in the biological process: synaptic vesicle endocytosis; maintenance of presynaptic active zone structure; regulation of synapse structure and activity.
13 alleles are reported.
The phenotype of these alleles is annotated with: presynaptic active zone.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Domain of unknown function DUF1866; Endonuclease/exonuclease/phosphatase; Inositol polyphosphate-related phosphatase; Nucleotide-binding, alpha-beta plait; Synaptojanin, N-terminal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes.