Flygut: an atlas of the Drosophila adult midgut

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Gene name Oatp58Dc
Flybase description The gene Organic anion transporting polypeptide 58Dc is referred to in FlyBase by the symbol Dmel\Oatp58Dc (CG3380, FBgn0034716).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.6811 -15.1273 -20.889177 -26.9303 -27.721787 -16.3358 -13.41902 -16.881383
    Affimetrix absolute value 5.974 3.743 3.799 3.643 3.978 4.645 4.904 4.214
    Affymetric present call in "x" number of chips 3 0 0 0 0 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sodium-independent organic anion transmembrane transporter activity; organic anion transmembrane transporter activity.
There is experimental evidence that it is involved in the biological process: response to methotrexate.
6 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Major facilitator superfamily domain, general substrate transporter; Organic anion transporter polypeptide OATP; Protease inhibitor, Kazal-type; Proteinase inhibitor I1, Kazal.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages.