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|Flybase description||The gene Sestrin is referred to in FlyBase by the symbol Dmel\Sesn (CG11299, FBgn0034897).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: inter-male aggressive behavior; regulation of reactive oxygen species metabolic process; mitochondrion degradation; multicellular organismal aging; negative regulation of cell growth.
12 alleles are reported.
The phenotypes of these alleles are annotated with: Z disc; myofibril; actomyosin; wing blade; sarcomere; mitochondrion; M band.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: PA26 p53-induced protein (sestrin).
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed at stages throughout the pupal period.