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|Flybase description||The gene yorkie is referred to in FlyBase by the symbol Dmel\yki (CG4005, FBgn0034970).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ubiquitin-protein ligase activity.
There is experimental evidence that it is involved in the biological process: cell proliferation; morphogenesis of an epithelial sheet; negative regulation of apoptosis; stem cell proliferation; cell competition in a multicellular organism; regulation of growth.
53 alleles are reported.
The phenotypes of these alleles are annotated with: eye disc; eye; wing disc; follicle cell; wing; adherens junction.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: WW/Rsp5/WWP.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.