Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name yki
Flybase description The gene yorkie is referred to in FlyBase by the symbol Dmel\yki (CG4005, FBgn0034970).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.2072 -1.4885 -2.231759 -2.2731 -4.186388 -2.4276 -3.03346 -3.276188
    Affimetrix absolute value 7.266 7.05 7.061 7.233 6.738 7.283 6.976 6.616
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: ubiquitin-protein ligase activity.
There is experimental evidence that it is involved in the biological process: cell proliferation; morphogenesis of an epithelial sheet; negative regulation of apoptosis; stem cell proliferation; cell competition in a multicellular organism; regulation of growth.
53 alleles are reported.
The phenotypes of these alleles are annotated with: eye disc; eye; wing disc; follicle cell; wing; adherens junction.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: WW/Rsp5/WWP.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.