Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Start1
Flybase description The gene Start1 is referred to in FlyBase by the symbol Dmel\Start1 (CG3522, FBgn0035028).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.0503 -1.2452 -1.502118 -1.9105 -1.749046 -1.3061 -3.14148 -1.709409
    Affimetrix absolute value 7.392 7.306 7.593 7.468 7.961 8.179 6.91 7.473
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: cholesterol binding; cholesterol transporter activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: steroid biosynthetic process.
3 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Lipid-binding START; MENTAL domain; START-like domain; Steroidogenic acute regulatory protein.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.