Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Mmp1
Flybase description The gene Matrix metalloproteinase 1 is referred to in FlyBase by the symbol Dmel\Mmp1 (CG4859, FBgn0035049).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.0854 1.786 1.243684 0.4306 -1.341399 1.2487 -0.40239 0.382694
    Affimetrix absolute value 4.825 8.405 8.489 8.511 8.348 8.877 8.452 8.31
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: metalloendopeptidase activity.
There is experimental evidence for 12 unique biological process terms, many of which group under: open tracheal system development; cellular component organization or biogenesis; growth; programmed cell death; developmental growth; cellular process; molting cycle, chitin-based cuticle; gland morphogenesis; biological regulation; post-embryonic organ morphogenesis; instar larval development.
31 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval trachea; embryonic/larval posterior spiracle; second instar larval cuticle; chaeta; embryonic/larval dorsal trunk; adult thoracic sensillum; mesothoracic tergum; third instar larva; embryonic/larval transverse connective.
It has 10 annotated transcripts and 10 annotated polypeptides.
Protein features are: Hemopexin/matrixin; Hemopexin/matrixin, conserved site; Hemopexin/matrixin, repeat; Metallopeptidase, catalytic domain; Peptidase M10, metallopeptidase; Peptidase M10A, matrix metallopeptidase; Peptidase M10A, matrix metallopeptidase, stromelysin type; Peptidase, metallopeptidase; Peptidoglycan binding-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed at stages throughout the pupal period.