|Home||Overview of gut regions||Anatomy||Histology||Transgene expression mapping||Gene expression|
|Search expression data by gene:|
|Flybase description||The gene Matrix metalloproteinase 1 is referred to in FlyBase by the symbol Dmel\Mmp1 (CG4859, FBgn0035049).|
|Expression data along the gut||
|Intestinal gene expression in different physiological conditions||
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
|Gene details (from Flybase)|| It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: metalloendopeptidase activity.
There is experimental evidence for 12 unique biological process terms, many of which group under: open tracheal system development; cellular component organization or biogenesis; growth; programmed cell death; developmental growth; cellular process; molting cycle, chitin-based cuticle; gland morphogenesis; biological regulation; post-embryonic organ morphogenesis; instar larval development.
31 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval trachea; embryonic/larval posterior spiracle; second instar larval cuticle; chaeta; embryonic/larval dorsal trunk; adult thoracic sensillum; mesothoracic tergum; third instar larva; embryonic/larval transverse connective.
It has 10 annotated transcripts and 10 annotated polypeptides.
Protein features are: Hemopexin/matrixin; Hemopexin/matrixin, conserved site; Hemopexin/matrixin, repeat; Metallopeptidase, catalytic domain; Peptidase M10, metallopeptidase; Peptidase M10A, matrix metallopeptidase; Peptidase M10A, matrix metallopeptidase, stromelysin type; Peptidase, metallopeptidase; Peptidoglycan binding-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression.
Peak expression observed at stages throughout the pupal period.